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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN14
All Species:
7.27
Human Site:
S681
Identified Species:
16
UniProt:
Q15678
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15678
NP_005392.2
1187
135261
S681
Q
G
P
P
E
E
G
S
G
S
H
E
V
P
Q
Chimpanzee
Pan troglodytes
XP_001171329
1187
135241
S681
Q
G
P
P
E
E
G
S
G
S
H
E
V
P
Q
Rhesus Macaque
Macaca mulatta
XP_001106167
1187
135194
P681
Q
G
P
P
E
E
G
P
G
S
H
E
V
P
Q
Dog
Lupus familis
XP_849236
1187
134903
P681
Q
G
P
P
E
E
V
P
G
S
H
E
A
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q62130
1189
135012
S681
T
L
R
E
Q
G
P
S
E
E
T
G
G
H
E
Rat
Rattus norvegicus
Q62728
1175
133393
T687
D
K
V
K
Q
E
G
T
E
E
Q
G
S
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511302
1193
135259
Q686
P
Q
E
A
G
S
M
Q
M
G
R
E
V
Q
Q
Chicken
Gallus gallus
XP_419419
1191
135566
Q686
V
Q
P
E
E
S
V
Q
M
G
H
E
V
Q
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339962
834
94004
S376
D
A
T
M
L
V
H
S
S
G
E
E
E
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
Q568
G
L
P
P
T
N
Q
Q
A
Y
N
T
S
S
P
Sea Urchin
Strong. purpuratus
XP_796215
1318
147575
A692
M
R
I
Q
D
Y
H
A
Q
V
G
M
Y
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
95.6
N.A.
91.5
53.7
N.A.
87.9
84.9
N.A.
32.8
N.A.
N.A.
N.A.
24.7
34.5
Protein Similarity:
100
99.7
99.5
97.2
N.A.
95.6
70.7
N.A.
92.1
91.5
N.A.
48.1
N.A.
N.A.
N.A.
42
51.7
P-Site Identity:
100
100
93.3
73.3
N.A.
6.6
13.3
N.A.
20
40
N.A.
13.3
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
20
26.6
N.A.
20
40
N.A.
13.3
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
10
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
19
46
46
0
0
19
19
10
64
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
37
0
0
10
10
37
0
37
28
10
19
10
10
10
% G
% His:
0
0
0
0
0
0
19
0
0
0
46
0
0
19
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
19
0
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
10
0
0
10
0
0
10
0
19
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% N
% Pro:
10
0
55
46
0
0
10
19
0
0
0
0
0
28
10
% P
% Gln:
37
19
0
10
19
0
10
28
10
0
10
0
0
19
55
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
10
% R
% Ser:
0
0
0
0
0
19
0
37
10
37
0
0
19
19
0
% S
% Thr:
10
0
10
0
10
0
0
10
0
0
10
10
0
0
0
% T
% Val:
10
0
10
0
0
10
19
0
0
10
0
0
46
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
10
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _